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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPE
All Species:
12.42
Human Site:
S2098
Identified Species:
22.78
UniProt:
Q02224
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02224
NP_001804.2
2701
316415
S2098
E
S
L
R
E
K
C
S
R
I
K
E
L
L
K
Chimpanzee
Pan troglodytes
XP_001170168
2701
316707
S2098
E
S
L
R
E
K
C
S
R
I
K
E
L
L
K
Rhesus Macaque
Macaca mulatta
XP_001110512
2701
316828
S2098
E
S
L
R
E
K
C
S
R
I
K
E
L
L
K
Dog
Lupus familis
XP_852631
1216
141588
K680
L
T
S
L
I
D
G
K
V
P
K
G
L
L
C
Cat
Felis silvestris
Mouse
Mus musculus
Q6RT24
2474
286506
E1937
R
E
K
C
F
R
I
E
K
L
L
K
R
Y
S
Rat
Rattus norvegicus
Q7TSP2
1385
159522
L849
L
Q
L
D
N
A
R
L
E
N
E
K
L
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420670
2150
248600
G1614
M
E
N
E
R
I
N
G
H
L
Q
S
L
L
N
Frog
Xenopus laevis
NP_001080954
2954
339950
E2295
S
E
L
Q
K
E
T
E
A
H
K
H
C
M
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524993
2013
231091
M1477
K
T
Q
E
Q
L
Q
M
E
S
L
T
R
D
Q
Honey Bee
Apis mellifera
XP_001121311
1418
164919
N882
I
E
Q
S
L
V
L
N
E
N
V
A
E
N
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781622
2537
290578
S1960
Q
Q
C
L
E
E
E
S
R
E
R
E
E
R
I
Poplar Tree
Populus trichocarpa
XP_002308893
1247
142380
N711
Q
S
F
S
S
I
S
N
A
I
S
D
F
K
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187629
1348
152938
S812
K
D
I
G
S
L
S
S
S
S
L
A
K
E
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.7
37.8
N.A.
60.5
21.2
N.A.
N.A.
37.1
31
N.A.
N.A.
26.1
24.8
N.A.
25.5
Protein Similarity:
100
99.2
98
42
N.A.
75
35.7
N.A.
N.A.
55
52.2
N.A.
N.A.
45.6
37.8
N.A.
48.8
P-Site Identity:
100
100
100
20
N.A.
0
20
N.A.
N.A.
13.3
13.3
N.A.
N.A.
0
0
N.A.
26.6
P-Site Similarity:
100
100
100
26.6
N.A.
26.6
40
N.A.
N.A.
26.6
40
N.A.
N.A.
26.6
6.6
N.A.
46.6
Percent
Protein Identity:
23.9
N.A.
N.A.
24.9
N.A.
N.A.
Protein Similarity:
34.6
N.A.
N.A.
37.6
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
16
0
0
16
0
0
8
% A
% Cys:
0
0
8
8
0
0
24
0
0
0
0
0
8
0
8
% C
% Asp:
0
8
0
8
0
8
0
0
0
0
0
8
0
8
8
% D
% Glu:
24
31
0
16
31
16
8
16
24
8
8
31
16
8
8
% E
% Phe:
0
0
8
0
8
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
8
0
0
8
8
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% H
% Ile:
8
0
8
0
8
16
8
0
0
31
0
0
0
0
8
% I
% Lys:
16
0
8
0
8
24
0
8
8
0
39
16
8
8
31
% K
% Leu:
16
0
39
16
8
16
8
8
0
16
24
0
47
47
8
% L
% Met:
8
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% M
% Asn:
0
0
8
0
8
0
8
16
0
16
0
0
0
8
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
16
16
16
8
8
0
8
0
0
0
8
0
0
0
8
% Q
% Arg:
8
0
0
24
8
8
8
0
31
0
8
0
16
8
0
% R
% Ser:
8
31
8
16
16
0
16
39
8
16
8
8
0
0
8
% S
% Thr:
0
16
0
0
0
0
8
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _